MyBioSource.com's MCOLN1 (ML4, Mucolipin-1, MG-2, Mucolipidin, MSTP080, TRP-ML1, TRPM-L1, TRPML1) is a Human, and Mouse Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The MCOLN1 (ML4, Mucolipin-1, MG-2, Mucolipidin, MSTP080, TRP-ML1, TRPM-L1, TRPML1) Antibody was generated using MCOLN1 as the antigen and it reacts with Human.
Description
This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV